PIVKA-II Antibody
Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinoma (HCC), γ-carboxylation of prothrombin is impaired so that PIVKA-II is formed instead of prothrombin. PIVKA-II is considered as is an efficient biomarker specific for HCC.
| Product： | PIVKA-II Monocal Antibody | |
| Cat: | DM-PIVKA-II-001 | |
| The Host of Origin: | Mouse IgG | |
| Method used: | A280nm E1%=14.0 | |
| Quantity: | 1.0mg,5mg, etc | |
| Quality: | Recognized H and chain | |
| Method used: | SDS-PAGE | |
| Buffer: | PBS(pH7.2 with 0.09%NaN3 | |
| Storage： | Refrigerate at -20℃,Avoid repeated freeze-throw cycles | |
| Expiry date: | More than 4 years | |
| Viral Testing: | Negative for HIV, HBsAg, HCV, STS | |
| Caution: | No test can guarantee a product to be non-infectious.Therefore,all material derived from human fluids be considered as potentially infectious. | |
| The Intended Use: | These biological products intended for technical purposes including pharmaceutical in vitro diagnostic and laboratory reagents. | |
| Product： | PIVKA-II Monocal Antibody（DCP） | |
| Cat: | DM-PIVKA-II-002 | |
| The Host of Origin: | Mouse IgG | |
| Method used: | A280nm E1%=14.0 | |
| Quantity: | 1.0mg,5mg etc | |
| Quality: | Recognized H and chain | |
| Method used: | SDS-PAGE | |
| Buffer: | PBS(pH7.2 with 0.09%NaN3 | |
| Storage： | Refrigerate at -20℃,Avoid repeated freeze-throw cycles | |
| Expiry date: | More than 4 year | |
| Viral Testing: | Negative for HIV, HBsAg, HCV, STS | |
| Caution: | No test can guarantee a product to be non-infectious.Therefore,all material derived from human fluids be considered as potentially infectious. | |
| The Intended Use: | These biological products intended for technical purposes including pharmaceutical in vitro diagnostic and laboratory reagents. | |